Peptide Stability Analysis Service

As an important tool for drug development, biotherapy, and molecular probes, the stability of peptides directly determines their functional performance and clinical application potential in vivo and in vitro. The stability problems of peptides mainly come from protease degradation, failure of chemical modification, changes in physical environment, and dynamic fluctuations of structure. CD ComputaBio relies on cutting-edge computational biology technology to provide customers with multi-dimensional and high-precision peptide stability analysis services, helping to optimize the design of candidate molecules and accelerate the R&D process.

Structural Characteristics of Peptides

Peptides are biological molecules composed of amino acid chains connected by amide bonds, and their stability is closely related to their unique structural characteristics.

Peptide Stability Analysis

Peptide stability analysis is a comprehensive technical means to systematically evaluate the chemical structure, biological activity, and functional integrity of peptide molecules in specific environments (such as high temperature, extreme pH, oxidative stress, etc.). The primary objective is to elucidate peptide degradation mechanisms (proteolysis, chemical modifications, and conformational fluctuations) and subsequently predict peptide lifespan, such as plasma half-life, and their stability under different application conditions. Although peptide stability analysis provides a theoretical basis for elucidating degradation mechanisms and predicting peptide lifespan, it still encounters numerous difficulties in practical applications.

Our Services

CD ComputaBio offers a suite of computational methods for peptide stability analysis. By utilizing molecular simulations, CD ComputaBio determines how environmental variations influence peptide charge, conformation, and stability, enabling you to pinpoint optimal conditions for your peptides. The computational chemistry tools allow CD ComputaBio to model chemical reactions that may affect peptide stability, including hydrolysis, oxidation, and deamidation. Our services are listed as follows, but are not limited to:

By Peptide Types

By Analysis Types

Software We Use

Our Advantages

• CD ComputaBio leverages deep learning and multivariate models for significantly higher prediction accuracy, reducing experimental costs.
• With no wet lab work required, CD ComputaBio delivers results in days, accelerating your drug discovery pipeline.
• Seamlessly integrates with protein engineering to facilitate multifunctional peptide development.

CD ComputaBio, at the forefront of computational biology, provides efficient and accurate peptide stability analysis using AI, molecular dynamics, and multi-dimensional modeling. CD ComputaBio predicts peptide degradation in environments ranging from plasma to extreme pH and identifies critical structural stability factors, all computationally. Whether it is for antimicrobial peptides, anticancer peptides, or delivery vectors, CD ComputaBio can provide verifiable computational solutions. If you are interested in our services or have any questions, please feel free to contact us.

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• Fusion Protein Modeling Service
• Membrane Protein Modeling Service
• Protein Modeling Service
• Receptor Protein Modeling Services
• GPCR Modeling Service