Time Series Co-expression Network Construction Service
Figure 1. Demo result of time series co-expression network construction service.
Demo result interpretation
The network diagram is the relationship between the screened core genes. The key genes are calculated by the method of graph theory, and their functions are predicted through the co-expression of the key genes.
Overall solutions
- We calculate the co-expression relationship between genes according to the change of gene expression signal value with time series, and obtain the expression regulation relationship and regulation direction between genes, so as to construct a gene expression regulation network.
- Using this network diagram, researchers can analyze the gene regulation ability to obtain the genes that the sample plays a regulatory role in the course of time.
The key steps to construct a co-expression network:
To understand the overall regulation relationship, choose all samples since there will be different disturbances among them that can better reflect the co-expression.
Or choose the sample related to a specific phenotype.
- Adjacency matrix construction
Since the goal is to build a co-expression network, it is necessary to find this "common", that is, to find the similarity of gene expression, so some algorithms for finding the similarity between genes are needed.
Time series co-expression network construction service
| Project name |
Time series co-expression network construction service |
| Samples requirement |
Our network analysis services in biology require you to provide specific requirements. |
| Timeline |
Decide according to your needs. |
| Deliverables |
We provide you with raw data and modeling results. |
| Price |
Inquiry |
Analysis requirements
Time, concentration, differential genes of samples with logical changes, genes selected by trend analysis or genes of interest.
Deliverables
- Picture files (Network diagrams), including png, PDF formats.
- Cytocape file: can be opened by cytoscape for detailed adjustment.
- Text file: Co-expression correlation and significance between genes, the order of gene core co-expression.
CD ComputaBio provides corresponding time series co-expression network construction service as proven to be very useful for understanding the biochemical basis of physiological events at different stages of drug development (even in different fields such as materials science). CD ComputaBio team has been working in this field for more than ten years and has published his findings in top scientific journals. If you have a need for network analysis services, please feel free to contact us.
We provide a variety of modeling services, but not limited to:
* For Research Use Only.
Related Services
