Peptide Drug Binding Affinity Calculation Service

What is Binding Affinity?

Binding affinity is the strength of the binding interaction between a single biomolecule to its ligand/binding partner. Binding affinity is typically measured and reported by the equilibrium dissociation constant (KD), which is used to evaluate and rank order strengths of bimolecular interactions. The smaller the KD value, the greater the binding affinity of the ligand for its target. The larger the KD value, the more weakly the target molecule and ligand are attracted to and bind to one another. Binding affinity is influenced by non-covalent intermolecular interactions such as hydrogen bonding, electrostatic interactions, hydrophobic and Van der Waals forces between the two molecules. In addition, binding affinity between a ligand and its target molecule may be affected by the presence of other molecules. Now, CD ComputaBio provides you with professional peptide drug binding affinity calculation service to meet your scientific research needs.

Overall solutions

• Provide you with professional peptide drug binding affinity calculation services. You can select the appropriate force field according to the needs of the system.
• Provide you with the calculation service of binding free energy. The calculation of binding free energy can evaluate the ligand-receptor affinity and provide a reference for drug design.
• Select the appropriate force field according to the needs of the system.
• Provide you with energy decomposition calculation services, which can help you determine the major amino acids that contribute to the receptor-ligand binding process. Molecular Mechanics Poisson–Boltzmann Surface Area (MM/PBSA) has been found to perform well in determining the effect of mutations on the association process and identifying hot spots in protein-protein complexes.

Why choose us?

• CD ComputaBio provides professional peptide drug binding affinity calculation service.
• CD ComputaBio will complete your project on time and efficiently. We have professional after-sales service. Provide customers with efficient and feasible solutions.
• CD ComputaBio cooperates with scientists from many pharmaceutical and biotechnology companies. We have a wealth of knowledge and experience to provide quality assurance services.

Our services

CD ComputaBio provides professional peptide drug binding affinity calculation service to meet the specific needs of our customers on time and on budget. CD ComputaBio relies on world-class technical expertise, we provide customers with the best quality one-stop peptide drug binding affinity calculation service, including the development of solutions according to different scientific research needs. Please feel free to contact us for more detailed information, our scientists will tailor the most reasonable plan for your project. If you want to know more service prices or technical details, please feel free to contact us.

• Peptide Molecular Dynamics Simulation
• Peptide Molecular Docking
• Peptide Homology Modeling Service
• Peptide Amino Acid Interaction Network Analysis
• Peptide Drug Energy Calculation Service
• Peptide Drug Target Validation Service