NMDS Analysis

What is NMDS Analysis?

The non-metric multidimensional scaling method is a data analysis method that reduces the research objects (samples or variables) in the multidimensional space to the low-dimensional space for positioning, analysis and classification, while retaining the original relationship between the objects. It is suitable for situations where precise similarity or dissimilarity data cannot be obtained between the research objects, but only the hierarchical relationship data between them can be obtained. Its basic feature is to treat the similarity or dissimilarity data between objects as a monotonic function of the distance between points. On the basis of maintaining the original data order relationship, replace the original data with new data columns of the same order for metric multi-dimensional scale analysis.

Overall solutions

The basic steps in a non-metric MDS algorithm are:

• Find a random configuration of points, e. g. by sampling from a normal distribution.
• Calculate the distances d between the points.
• Find the optimal monotonic transformation of the proximities, in order to obtain optimally scaled data f(x).
• Minimize the stress between the optimally scaled data and the distances by finding a new configuration of points.
• Compare the stress to some criterion. If the stress is small enough then exit the algorithm else return to 2.

Software and algorithm

Qiime calculates the beta diversity distance matrix, and the R language vegan software package is used for NMDS analysis and mapping.

Our advantages

• From the beginning to the completion of the project, we are committed to providing timely and high-quality services.
• Our team works with scientists, quality assurance/quality control professionals and project managers from many pharmaceutical and biotechnology companies and organizations around the world, and has a wealth of knowledge and experience.
• Our well-trained, friendly and professional research supervisors and project managers will complete your project on time through open communication channels and meet your requirements.

Our services

CD ComputaBio' NMDS analysis service can significantly reduce the cost and labor of the subsequent experiments. NMDS analysis service is a personalized and customized innovative scientific research service. Each project needs to be evaluated before the corresponding analysis plan and price can be determined. If you want to know more about service prices or technical details, please feel free to contact us.

Reference:

1. Rivas M N, Burton O T, Wise P, et al. A microbiota signature associated with experimental food allergy promotes allergic sensitization and anaphylaxis. J Allergy Clin Immunol, 2013, 131(1):201-212.

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