LEfSe Analysis Service

LEfSe (Linear discriminant analysis Effect Size) determines the features (organisms, clades, operational taxonomic units, genes, or functions) most likely to explain differences between classes by coupling standard tests for statistical significance with additional tests encoding biological consistency and effect relevance. Now, CD ComputaBio offers LEfSe analysis service to meet the specific needs of different customers.

Overall solutions

CD ComputaBio offer LEfSe analysis service, which can be used to discover high-dimensional biomarkers and reveal genomic characteristics, including genes, metabolism and classification, used to distinguish two or more biological conditions. The algorithm emphasizes statistical significance and biological relevance. Allows researchers to identify features of different abundances and associated categories.

Software

Analysis software: LEfSE. According to the taxonomic composition, perform linear discriminant analysis (LDA) on the samples according to different grouping conditions to find out the communities or species that have significant differences in the division of the samples.

Why choose us?

• The LEfSe service provided by CD ComputaBio can maximize the inter-class scatter matrix of pattern samples after projection, and at the same time minimize the intra-class scatter matrix. In other words, it can ensure that the model samples after projection have the smallest intra-class distance and the largest inter-class distance in the new space, that is, the model has the best separability in the space.
• CD ComputaBio has extensive knowledge and experience in LEfSe analysis service. We have collaborated with many biotech companies and many scientists in research institutes. We have rich experience in this area to meet your scientific research needs.
• CD ComputaBio will complete your project on time and efficiently and meet your requirements.
• CD ComputaBio has established a professional after-sales service team to provide customers with efficient, fast, practical and feasible solutions.

Our services

CD ComputaBio provides professional LEfSe analysis service to meet the needs of regular customers to determine hits on time and on budget. CD ComputaBio relies on the world-class technical expertise, we provide customers with the best quality one-stop LEfSe analysis service, including the development of experimental procedures according to different experimental needs. Please feel free to contact us for more detailed information, our scientists will tailor the most reasonable plan for your project. If you want to know more about service prices or technical details, please feel free to contact us.

Reference:

1. Segata N, Izard J, Waldron L, Gevers D, Miropolsky L.; et al. Metagenomic biomarker discovery and explanation. Genome Biol. 2011. 12: R60.

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