Antibody Structure Prediction

Predicting the three-dimensional structure of an antibody is very important for antibody engineering including optimizing antibody affinity, specificity and stability. The most important part of antibody structure prediction is to predict the structure of antibody variable fragments (Fv), because the constant regions of antibodies are actually similar in all antibodies of the same isotype. Fv consists of two chains, a heavy chain variable domain (VL) and a light chain variable domain (VH). Each chain contains three hypervariable complementarity determining regions (CDR) that determine the interaction with the antigen. Because the framework regions of VL and VH domains are extremely conservative, the research of Fv structure prediction mainly focuses on the prediction of 6 CDR loops. Currently, CD ComputaBio can provide many methods for predicting antibody structure. We use sequence homology with natural antibody structure to select the backbone for modeling. If you have any needs in this regard, you can contact us at any time.

Overall solutions

• CD ComputaBio uses various antibody structure prediction methods to help customers predict the structure of Fv and CDR, thereby facilitating their antibody engineering plans.
• With rich experience in antibody structure prediction, we have the ability to customize different antibody structure prediction strategies according to the specific requirements of customers. We ensure to provide the best predictive structural model of Fv and CDRs models, which can be used to design and engineer antibodies with desired characteristics.

Why choose us?

• CD ComputaBio has extensive knowledge and experience in antibody structure prediction.
• CD ComputaBio will complete your project on time and efficiently and meet your requirements.
• CD ComputaBio has established a professional after-sales service team to provide customers with efficient, fast, practical and feasible solutions.

Our services

CD ComputaBio provides professional antibody structure prediction service to meet the specific needs of regular customers on time and according to budget. CD ComputaBio relies on world-class technical expertise, we provide customers with the best quality one-stop antibody structure prediction service, including the development of scientific procedures according to different solution needs. Please feel free to contact us for more detailed information, our scientists will tailor the most reasonable plan for your project. If you want to know more service prices or technical details, please feel free to contact us.

• Antibody Modeling Services
• Antibody Design/Humanization Service
• Antigenic Determinant Prediction
• Antibody Affinity Maturation Service
• Computer-Aided Antibody Screening and Design
• Antibody Reformatting Service