Antibody Allosteric Effect Service

Allostery is a regulated biological process through which the binding effect of macromolecules at one site is transferred to another site. Although monoclonal antibodies (mAbs) are highly specific in terms of biological activity, they also exhibit allosteric effects. These allosteric effects will cause the conformation of the antigen to change, thereby affecting its biological activity and interaction with other mAbs. Generally speaking, the allosteric effects of antibodies can be divided into negative allosteric effects and positive allosteric effects. As a leading provider of excellent antibody development services, CD ComputaBio provides a complete antibody service portfolio, including antibody stability design, allosteric effect analysis, de novo design, modular antibody design, etc. Our expert staff can help you at every stage of antibody development.

Overall solutions

• Over the years, CD ComputaBio has developed a variety of methods to study the allosteric effects of antibodies and their applications in different scientific fields, such as conformational mechanisms, drug discovery, and various diseases.
• We provide a wide range of antibody allosteric effect analysis services to help our customers understand the physical and chemical properties, biological activities, affinity and stability of their candidate monoclonal antibodies.
• CD ComputaBio can start from the analysis of antibody structure and solve a series of problems such as the theoretical design of antibodies.

Why choose us?

• Our antibody allosteric effect service can significantly reduce the burden of new therapeutic antibodies and proteins, and provide a more effective way for clinical research.
• CD ComputaBio's antibody allosteric effect service shows a significant reduction in aggregation tendency while maintaining antigen binding.
• CD ComputaBio has established a professional after-sales service team to provide customers with efficient, fast, practical and feasible solutions.
• CD ComputaBio has in-depth cooperation with many pharmaceutical companies and research institutes, and has extensive experience in providing them with high-quality services.

Our services

CD ComputaBio provides professional antibody allosteric effect service to meet the specific needs of regular customers on time and according to budget. CD ComputaBio relies on world-class technical expertise, we provide customers with the best quality one-stop antibody allosteric effect service, including the development of scientific procedures according to different experimental needs. Please feel free to contact us for more detailed information, our scientists will tailor the most reasonable plan for your project. If you want to know more service prices or technical details, please feel free to contact us.

• Antibody Modeling Services
• Antibody Design/Humanization Service
• Antigenic Determinant Prediction
• Antibody Affinity Maturation Service
• Computer-Aided Antibody Screening and Design
• Antibody Reformatting Service