Leukotriene D 4 (LTD 4) is a type of leukotrienes. Its main function in the body is to induce smooth muscle contraction, which leads to bronchoconstriction and vasoconstriction. It also increases vascular permeability. LTD 4 is released by basophils. Other leukotrienes that function in a similar fashion are the leukotrienes C4 and E4. Agents that inhibit the function of these leukotrienes are leukotriene receptor antagonists (eg, zafirlukast, montelukast) and are useful in asthmatics. CD ComputaBio now offers professional LTD4 targeting services to meet your research needs.
Our Services
- LTD4 Inhibitor Design Service
We provide design services for LTD4 small molecule inhibitors, and we also provide design services for peptide inhibitors. For designed compounds, we offer further structural optimization and screening services. We provide inhibitor molecular docking (LTD4-small molecule inhibitor docking and LTD4-peptide inhibitor docking) and molecular dynamics simulation services to select appropriate simulation conditions such as molecular dynamics simulation force fields for you.
- Pharmacophore Model Construction Service
Our pharmacophore model construction service can help discover the key pharmacodynamic characteristics of drug molecules, establish a clear structure-activity relationship, conduct virtual screening of compound libraries through the method of pharmacophore, and find new drugs that are active on the target. Skeletal compounds. Target prediction by pharmacophore to predict the pharmacological action spectrum of the compound. By using pharmacophore models, major adverse reactions can be predicted early in drug development, thereby reducing the probability of drug development failure.
- Biological Data Analysis
We provide comprehensive biological data analysis services, and our team creates an efficient data analysis pipeline that combines mathematics, statistics and programming to perform the required analysis for a client's specific technical or biological research question. Our goal is to enable researchers to make meaningful observations and discoveries from the vast amounts of data analyzed by the target。
Our Capabilities
CD ComputaBio offers you a variety of target analysis service types to choose from. Our experts have extensive experience in the field and have successfully completed several projects. We will complete your project on time and efficiently. Our researchers can quickly understand the project situation through a simple description, and quickly develop a feasible research plan according to customer needs. If you would like to know more about the LTD4 targeting services provided by CD ComputaBio, please feel free to contact us.
Our Protein Structure Modeling Service Targeting LTD4
CD ComputaBio uses computational modeling to predict the three-dimensional structure of proteins. We have extensive experience in modeling various proteins. The resulting structural models are all quality-validated and can be used for a variety of purposes, such as annotating genes with unknown functions and structure-based drug design. Structural modeling programs also work seamlessly with downstream computational modeling protocols, including docking and molecular dynamics simulations. We provide the following protein structure modeling services for you to choose from:
- Fold Recognition Service
- Fusion Protein Modeling Service
- Homology Modeling Service
- Membrane Protein Modeling Service
- Antibody Modeling Service
* For Research Use Only.
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