Genomics is a cornerstone of modern biology, providing insights into the structure, function, and evolution of genomes. CD ComputaBio's genomics services leverage advanced computational tools and expertise to analyze genomic data, enabling researchers to uncover genetic variations, understand disease mechanisms, and develop personalized therapies. From data preparation to result visualization, our services cover the entire genomics workflow, ensuring accurate and actionable insights.
Introduction to Genomics
Genomics involves the study of an organism's complete set of DNA, including genes and non-coding regions. With the advent of high-throughput sequencing methods, vast amounts of genomic data are generated, requiring sophisticated computational methods for analysis. Genomics plays a critical role in understanding genetic diversity, identifying disease-associated variants, and exploring evolutionary relationships. By integrating genomic data with other omics data, researchers can gain a comprehensive view of biological systems and advance discoveries in life sciences and medicine.
Figure 1. Computational Strategy for Genomics. (Sardi M, et al., 2021)
Research Areas of Genomics
Functional Genomics
Functional genomics focuses on dynamic aspects such as gene transcription, translation, and protein-protein interactions, rather than static aspects of genomic information, such as DNA sequence.
Pharmacogenomics
Explores the relationship between an individual's genome and their response to drugs, enabling personalized medicine and the development of more effective and safer drugs.
Metagenomics
Metagenomics studies the genomes of microbial communities in various environments. The field helps us understand the diversity, structure and function of microbial communities and their role in ecological processes.
Our Services
Computational biology plays a vital role in genomics, which uses computational tools and algorithms to analyze and interpret massive amounts of data. Our expertise in computational biology supports us in adopting efficient analysis processes, we can provide accurate and comprehensive genomic data analysis, providing a solid foundation for research.
By Workflow
Data Preparation and Processing: Starting with experimental data acquisition, perform quality control, data cleaning and format conversion to prepare for subsequent analysis.
Sequence Alignment: Use advanced alignment algorithms to align sequencing reads with reference genomes to ensure high accuracy and summary.
Genome Assembly: Multiple assembly methods can be performed to reconstruct genome sequences, including whole genome assembly and specific region assembly.
Genomic Data Analysis: Analyze genomic data to identify patterns and relationships. Uncover crucial information like gene-regulatory networks, the co-expression of genes under different conditions, and the impact of genetic variations on phenotypes.
Result Visualization: Use visualization tools to generate clear graphics and reports to help researchers better understand and present analysis results.
Genotyping Services and Pharmacogenomics
From SNP analysis to genome-wide association studies, CD ComputaBio performs
- Scalable Genotyping
- Targeted Sequencing
- Pharmacogenomic Analyses
- Whole Exome Sequencing
Genomic Data Analysis
To maximize your investment in generating accurate, reliable data and quality control, we provide you with the best genomics data analysis services to support your drug discovery, preclinical and clinical research.
- De Novo Sequencing Data Analysis
- Genome Resequencing Data Analysis
- Metagenomic Sequencing Data Analysis
- Annotation and Gene Prediction
- Targeted & Exome Sequencing Data Analysis
- More
Our Advantages
Advanced Computational Tools
State-of-the-art software and algorithms ensure accurate and reliable analysis of genomic data.
Expert Team
A team of computational biologists, bioinformaticians, and geneticists provides tailored solutions for each project.
Customized Approaches
Services are adapted to meet specific project requirements, from data preparation to result visualization.
CD ComputaBio's genomics service provides comprehensive computational tools and expertise to accelerate the discovery of new therapeutics. By leveraging advanced genomics methods, the service is able to efficiently provide you with relevant analysis services. If you are interested in our services or have any questions, please feel free to contact us.
Reference:
- Sardi M, Gasch A P. Incorporating comparative genomics into the design–test–learn cycle of microbial strain engineering. FEMS Yeast Research, 2021, 17(5): fox042.
* For Research Use Only.
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