Antibody Affinity Modification Services

CD ComputaBio specializes in cutting-edge solutions for enhancing antibody affinity and specificity, enabling researchers and scientists to achieve superior results in their experiments and assays. With advanced algorithms, innovative methods, and comprehensive services, we are your trusted partner for antibody affinity modification.

• Affinity Maturation: We offer affinity maturation services to optimize the binding affinity of antibodies. Through a rational design and iterative selection process, we can generate high-affinity antibodies with better binding kinetics for your specific target.
• Epitope Mapping: Our epitope mapping service helps to identify the precise binding site of the antibody on the target antigen. This information is critical for understanding antibody-antigen interactions and designing targeted therapies.
• Affinity Purification: We provide affinity purification services to isolate and enrich antibodies that are highly specific to the target antigen. This ensures that unwanted cross-reactivity and impurities are removed, resulting in pure, highly specific antibodies.

Feature Services Items

• Antibody Humanization: We specialize in humanizing antibodies of non-human origin to reduce their immunogenicity and increase their compatibility for therapeutic applications.
• Antibody Conjugation: Our conjugation service allows for the attachment of various molecules, such as fluorescent dyes or toxins, to antibodies. In this way, antibodies can be used for imaging, diagnostics, or targeted therapies.
• Phage Display: By fusing antibody genes to phages, we can create antibody libraries and screen them to identify clones with greater affinity for the target antigen. This method allows for rapid screening of a large number of antibody variants.

Our Methods

We use a variety of methods and techniques to modify the affinity of antibodies:

•  Directed Evolution: This is a powerful technique that involves generating diverse libraries of antibody variants and selectively amplifying antibodies with higher affinity. This method utilizes random mutagenesis followed by a screening or selection process to identify high-affinity antibodies.
• Protein Engineering: Our experts utilize rational design strategies to engineer antibody sequences, introducing targeted mutations to enhance their affinity for target antigens. By utilizing structural information and computational modeling, we can precisely modify antibodies to optimize antibody binding.

Algorithms

We have developed advanced algorithms that use computational modeling, molecular simulation, and artificial intelligence to guide our affinity modification process. These algorithms enable us to predict and optimize antibody-antigen interactions and accelerate the design and development of high-affinity antibodies.

Features

• With our antibody affinity modification services, you can expect to benefit from our extensive expertise and state-of-the-art technologies. We have successfully modified antibody affinities for various research fields, including therapeutic development, diagnostics, and basic research.
• Customized Solutions: We understand that each project is unique, and our team of experts works closely with you to develop customized strategies that address your specific requirements and goals.

Why Choose Us?

Partner with us to utilize our antibody affinity modification services to improve the effectiveness and accuracy of your research or therapeutic programs. Our experienced team, cutting-edge technology, and commitment to excellence make us your ideal partner for antibody engineering and optimization. Contact us today to discuss your specific project requirements and let our antibody affinity modification services help you achieve remarkable results.

• Antibody Drug Immobilization Site Modification